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As mentioned in the forum, I've been able to use such older ISO files directly inside a VM (Windows NT 4 in this case) running an old copy of Clone CD (version 184.108.40.206 from the year 2002) that implements its own virtual CD drive inside the VM. This was after having such an ISO fail to be recognized as such under modern copies of PowerISO or WinRAR, or indeed the VMWare driver (all of which will usually read anything).